%0 Journal Article 
%T Estudio de dosis flexibles de paliperidona ER en pacientes con esquizofrenia previamente tratados sin efectividad con otros antipsicóticos
%D 2012
%@ 0034-7450
%U http://hdl.handle.net/10906/81210
%X Background

Extended-release (ER) paliperidone is an innovative atypical antipsychotic that allows minimal peak-to-through fluctuations with once-daily dosing.
Objective

To evaluate effectiveness, safety and tolerability of flexible, once-daily doses of paliperidone ER (3–12 mg/day) in patients with schizophrenia from Argentina and Colombia who had previously failed treatment with other antipsychotic agents.
Methods

The authors conducted a 6-month, open-label, prospective and multicentric study. Effectiveness was assessed with Positive and Negative Syndrome Scale (PANSS) and Personal and Social Performance scale (PSP). Other measures of effectiveness, safety and tolerability, were also conducted.
%K Ciencias  socio biomédicas
%K Medical sciences
%K Esquizofrenia
%K Paliperidona ER
%K Tolerancia
%K Seguridad
%~ GOEDOC, SUB GOETTINGEN