%0 Journal Article 
%T Moebius Syndrome, Ventricular Septal Defect Due To Prenatal Exposure To Misoprostol
%D 2013
%@ 0370-4106
%U http://hdl.handle.net/10906/81229
%X Introduction: Moebius syndrome/sequence is characterized by facial and abducens nerve damage and may be associated with congenital orofacial and limb defects. Additionally, in the last two decades, a possible association with prenatal exposure to misoprostol has been reported. Objective: To present a case of Moebius Syndrome with complex heart disease (ventricular septal defect and pseudocoarctation of the aorta) associated with prenatal exposure to misoprostol. Case report: A 5 year old patient diagnosed with Moebius Syndrome who consulted specialists due to psychomotor retardation, craniofacial, heart and limb defects, and with a history of prenatal exposure to misoprostol is presented. Conclusions: Although the etiology of this syndrome is not clear, hypoxia is a pathophysiological mechanism involved, which can be secondary to prenatal exposure to misoprostol.
%K Misoprostol
%K Sindrome de Moebius
%K Ciencias socio biomédicas
%K Medical sciences
%~ GOEDOC, SUB GOETTINGEN