TY  - JOUR 
TI  - Efficacy and safety of oral low-dose glucocorticoids in patients with estrogen-dependent primary osteoarthritis
JO  - Rheumatology International;  Vol. 34  No. 5
PB  - Springer Verlag
PY  - 2014
issn 1437-160X
AB  - Estrogen-dependent osteoarthritis (EDPOA) is a disease of perimenopausal-age women. Their manifestations are polyarticular pain with common co-morbidities (carpal tunnel syndrome, insomnia, fatigue, depression, and fibromyalgia). Based on dual role of glucocorticoids, its trophic action on the chondrocyte and its anti-inflammatory effect, we conducted a prospective interventional cohort study where we evaluate the efficacy and safety of oral low-dose GC in one hundred women with EDPOA. The pain intensity, number of tender joints as well as impact in co-morbidities were analyzed. We conclude that the use of low-dose GC in patients with EDPOA can be an effective and a safe therapeutic option. © 2013 Springer-Verlag.
KW  - Ciencias  socio biomédicas
KW  - Medical sciences
KW  - Esteroides
KW  - Menopausia
KW  - Menopause
KW  - Steroids
KW  - Biomedical sciences
UR  - http://hdl.handle.net/10906/78521
ER  -