TY  - JOUR 
TI  - Moebius Syndrome, Ventricular Septal Defect Due To Prenatal Exposure To Misoprostol
PB  - Sociedad Chilena de Pediatría
PY  - 2013
issn 0370-4106
AB  - Introduction: Moebius syndrome/sequence is characterized by facial and abducens nerve damage and may be associated with congenital orofacial and limb defects. Additionally, in the last two decades, a possible association with prenatal exposure to misoprostol has been reported. Objective: To present a case of Moebius Syndrome with complex heart disease (ventricular septal defect and pseudocoarctation of the aorta) associated with prenatal exposure to misoprostol. Case report: A 5 year old patient diagnosed with Moebius Syndrome who consulted specialists due to psychomotor retardation, craniofacial, heart and limb defects, and with a history of prenatal exposure to misoprostol is presented. Conclusions: Although the etiology of this syndrome is not clear, hypoxia is a pathophysiological mechanism involved, which can be secondary to prenatal exposure to misoprostol.
KW  - Misoprostol
KW  - Sindrome de Moebius
KW  - Ciencias socio biomédicas
KW  - Medical sciences
UR  - http://hdl.handle.net/10906/81229
ER  -