%0 Journal Article %T Effects of fluids on microvascular perfusion in patients with severe sepsis %D 2010 %U http://hdl.handle.net/10906/81205 %X Purpose To evaluate the effects of fluid administration on microcirculatory alterations in sepsis. Methods With a Sidestream Dark Field device, we evaluated the effects of fluids on the sublingual microcirculation in 60 patients with severe sepsis. These patients were investigated either within 24 h (early, n = 37) or more than 48 h (late, n = 23) after a diagnosis of severe sepsis. Hemodynamic and microcirculatory measurements were obtained before and 30 min after administration of 1,000 ml Ringer’s lactate (n = 29) or 400 ml 4% albumin (n = 31) solutions. %K Microcirculación %K Coloides %K Cristaloides y coloides %K Sepsis %~ GOEDOC, SUB GOETTINGEN