%0 Journal Article 
%T Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
%D 2012
%@ 0908-665X
%U http://hdl.handle.net/10906/78507
%X BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7 costimulatory pathway blockade in comparison with CD154 blockade.
%K Ciencias socio biomédicas
%K Medical sciences
%K Anticuerpos
%K Trasplante
%K Arteria
%K Xenotrasplantes
%~ GOEDOC, SUB GOETTINGEN