TY  - JOUR 
TI  - Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
PB  - Wiley
PY  - 2012
issn 0908-665X
AB  - BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7 costimulatory pathway blockade in comparison with CD154 blockade.
KW  - Ciencias socio biomédicas
KW  - Medical sciences
KW  - Anticuerpos
KW  - Trasplante
KW  - Arteria
KW  - Xenotrasplantes
UR  - http://hdl.handle.net/10906/78507
ER  -