Nuevo conocimiento - FVL

URI permanente para esta colecciónhttp://hdl.handle.net/10906/81422

Examinar

Mostrando 1 - 20 de 22

Adipocitos, obesidad visceral, inflamación y enfermedad cardiovascular
(Sociedad Colombianade Cardiología, 2010-10-01) Manzur, Fernando
La obesidad es un importante problema de salud a nivel mundial. Se considera el resultado de la combinación de factores genéticos, alimentación inadecuada y falta de actividad física regular. La ingestión de una dieta de alta densidad energética, es la principal causa de obesidad visceral o central, ya que el exceso de energía se almacena en los adipocitos, que aumentan en tamaño y en número, o ambos, en especial los viscerales, produciendo un incremento en la tasa de lipólisis, que a su vez, estimula la secreción de citoquinas por leucocitos, macrófagos y adipocitos, y conduce a estado proinflamatorio, resistencia a la insulina y disfunción endotelial. Esta última, favorecida por el proceso inflamatorio, puede ser el vínculo de unión entre la obesidad y la enfermedad cardiovascular. Así, la disfunción del tejido adiposo representa el mecanismo etiopatogénico en el desarrollo de enfermedad cardiovascular, iniciado por la obesidad visceral.
Alergia : abordaje clínico, diagnóstico y tratamiento
(Médica Panamericana, 2010-01-01) Cardona Villa, Ricardo
El contenido de esta obra trata de abarcar la mayor parte de temas posible, distribuyéndolos en diferentes módulos, desde los aspectos básicos inmunológicos y moleculares hasta los diferentes síndromes clínicos, pasando por temas de gran actualidad científica e interés general. Un objetivo importante es que la obra contribuya a la unificación de criterios, sin caer en dogmatismos, fortaleciendo de esta forma un enfoque “iberoamericano” pero que invite a la discusión y al debate.
Anaphylaxis in Latin America: a report of the online Latin American survey on anaphylaxis (OLASA).
(University of São Paulo, 2011-01-01) Adaci Coelho, Magna
Of all patients, 68.5% were older than 18 years, 41.6% were male, and 65.4% experienced the allergic reaction at home. The etiologic agent was identified in 87.4% of cases and predominantly consisted of drugs (31.2%), foods (23.3%), and insect stings (14.9%). The main symptom categories observed during the acute episodes were cutaneous (94.0%) and respiratory (79.0%). The majority of patients (71.6%) were treated initially by a physician (office/emergency room) within the first hour after the reaction occurred (60.2%), and 43.5% recovered in the first hour after treatment. Most patients were treated in an emergency setting, but only 37.3% received parenteral epinephrine alone or associated with other medication. However, 80.5% and 70.2% were treated with corticosteroids or antihistamines (alone or in association), respectively. A total of 12.9% of the patients underwent reanimation maneuvers, and 15.2% were hospitalized. Only 5.8% of the patients returned to the emergency room after discharge, with 21.7% returning in the first 6 hours after initial treatment.
Desenlaces clínicos en una cohorte de pacientes con síndrome coronario agudo y administración intracoronaria de tirofiban
(Elsevier, 2015-01-01) Carrillo Gómez, Diana Cristina
Introduction: Glycoprotein IIb/IIIa receptor inhibitors reduce major adverse cardiovascularevents (MACE) in patients with acute coronary syndrome.Objective: To determine the major adverse cardiovascular events and safety of intracoronaryand intravenous tirofiban in patients with acute coronary syndrome with percutaneous coronaryintervention (PCI) compared to a group of patients without this medication.Material and methods:Prospective cohort. Adults with acute coronary syndrome from January2010 to December 2012 were included. A proportional hazard regression model after 1 monthof follow up where the risk of MACE and the interest variable was intracoronary and intravenoustirofiban were assessed.Results: 382 patients were included. 46% (174 patients) received intracoronary tirofiban. Theaverage age was 65 years vs. 60 years in the group of non-tirofiban users (p = 0.00). The rate ofMACE at the first month was od 13/1000 events and 15/1000 events respectively in the grouptirofiban and non-tirofiban (log rank test 0,935). The tirofiban use was neither related to a lowerincidence of MACE (HR 1.09 95% IC 0.72 1.65) nor to major bleeding after the first month offollow up (1.72% vs. 2.88% respectively, p = 0.456).Conclusions: Intracoronary and intravenous tirofiban in patients with acute coronary syndromewas neither related to lower incidence of MACE nor to bleeding events; however, it should betaken into account that other clinical variables and the severity of unquantified coronary eventsmight influence the results. © 2015 Sociedad Colombiana de Cardiología y Cirugía Cardiovascular.
Echocardiographic assessment of valve prostheses in the pediatric population
(Sociedad Colombiana de Cardiologia y Cirugia Cardiovascular, 2014-01-01) Santos, Raúl D.
En niños con insuficiencia o estenosis valvular significativa, la intervención de la válvula, ya sea valvuloplastia o reemplazo valvular, suele ser inevitable. El seguimiento de estos pacientes puede ser complejo; los síntomas iniciales de disfunción valvular protésica son inespecíficos y en ocasiones es difícil diferenciar entre los efectos de la disfunción valvular, las patologías no cardíacas, la disfunción ventricular y la hipertensión pulmonar. Aunque el examen físico puede alertar al clínico acerca de alteraciones, se requieren otros métodos diagnósticos para evaluar la función de la prótesis. La ecocardiografía Doppler es el método de elección no invasivo para estudiar la función valvular y pese a que muchas de las mediciones y parámetros de normalidad y anormalidad son extrapolados de estudios en adultos, se han tratado de definir estándares en pacientes pediátricos. Este documento ofrece una revisión acerca de las técnicas usadas en el estudio de las válvulas protésicas con base en literatura científica, consensos internacionales y opiniones de expertos.
Effect of regular aerobic exercise on endothelium-dependent vasodilation in pregnant women. A randomized controlled trial
(Lippincott, Williams & Wilkins, 2012-05-15) Ramiíez Vélez, Robinson
Este documento del doctor Robinson Ramiíez Vélez, especializado en Niveles de actividad física, Condición física y tiempo, vinculado a Colciencias a través de sus investigaciones. Articulista de publicaciones sobre medicina entre ellos Caracteristicas antropométicas y Funcionales de individuos físicamente activos, Percentiles de presión arterial de niños y adolescentes de Santiago de Cali Colombia, Condición física, actividad física y dificultades para su realización en estudiantes de medicina y otros más que también incluye la investigación Efecto del ejercicio aeróbico regular sobre la vasodilatación dependiente del endotelio en mujeres embarazadas. Un ensayo controlado aleatorio.
Effects Of Endurance Training On Expression Endothelial Nitric Oxide Synthase And Nitric Oxide Production In Human Placenta
(Lippincott Williams & Wilkins, 2013-12-14) Ramírez Vélez, Robinson; Bustamante, Juanita; Czerniczyniec, Analia; Aguilar de Plata, Ana C.; Lores Arnaiz, Silvia
To determine the effects of combined aerobic and resistance exercise training during the second half of pregnancy on endothelial NOS expression (eNOS), nitric oxide (NO) production and oxygen metabolism in human placenta.
Epidemiology of diabetes mellitus in South America: The experience of Colombia
(Elsevier Doyma, 2016-09-01) Vargas-Uricoechea, Hernando
According to the International Diabetes Federation, 8.3% of the world population suffers from diabetes mellitus, and it is expected that the number of individuals with the disease will increase to over 592 million. In South and Central America, it is estimated that the increase in the number of cases diagnosed in the period from 2013 to 2035 will be 59.8% (from 24 to 38.5 millions). According to the World Health Organisation, the prevalence of fasting hyperglycaemia in the region of the Americas in 2014 was 9.3% in men and 8.1% in women. The countries with the highest prevalence of diabetes mellitus in adults ≥ 18 years were: Guyana, Surinam, Chile, and Argentina. In Colombia, the prevalence of type 2 diabetes mellitus is variable, depending on the population range assessed and the diagnostic criteria used. © 2016 Sociedad Española de Arteriosclerosis
Hyperferritinemic syndrome: Still’s disease and catastrophic antiphospholipid syndrome triggered by fulminant Chikungunya infection: a case report of two patients
(Springer-Verlag London Ltd, 2015-08-02) Echeverry, Alex A.
There are four medical conditions characterized by high levels of ferritin, the macrophage activation syndrome (MAS), adult onset Still’ s disease (AOSD), catastrophic antiphospholipid syndrome (CAPS), and septic shock, that share similar clinical and laboratory features, suggesting a common pathogenic mechanism. This common syndrome entity is termed “the hyperferritinemic syndrome.” Here, we describe two different cases of hyperferritinemic syndrome triggered by Chikungunya fever virus infection: a 21-year-old female with SLE and a 32-year-old male patient who developed AOSD after the coinfection of dengue and Chikungunya viruses.
Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion
(BioMed Central, 2015-04-22) Ospina Tascon, Gustavo Adolfo
NTRODUCTION: Although the prognostic value of persistent hyperlactatemia in septic shock is unequivocal, its physiological determinants are controversial. Particularly, the role of impaired hepatic clearance has been underestimated and is only considered relevant in patients with liver ischemia or cirrhosis. Our objectives were to establish whether endotoxemia impairs whole body net lactate clearance, and to explore a potential role for total liver hypoperfusion during the early phase of septic shock.
In Utero Fetal Programming And Its Impact On Health In Adulthood
(Elsevier Espana, 2012-06-01) Ramírez Vélez, Robinson
Cambios metabólicos in útero establecen patrones fisiológicos y estructurales a largo plazo que pueden «programar» la salud durante la vida adulta, teoría popularmente conocida como «Hipótesis de Barker». Evidencia experimental y clínica sugiere que patologías como hipertensión arterial, enfermedad isquémica coronaria, síndrome metabólico y diabetes mellitus tipo 2, pueden «programarse» durante las primeras etapas del desarrollo fetal y manifestarse en etapas tardías, al interactuar con el estilo de vida y otros factores de riesgo adquiridos convencionales con el medio ambiente. El objetivo de esta revisión es presentar evidencia adicional y actualizada que apoyen la asociación entre la salud fetal intrauterina y el aumento en la prevalencia de enfermedades crónicas no transmisibles en la edad adulta. La función endotelial, el estrés oxidativo, la resistencia a la insulina, y la función mitocondrial son tratadas como posibles mecanismos celulares y moleculares.
Mid-Term frequency domain scheduler for resource allocation in wireless mobile communications systems.
(Elsevier Science, 2017-01-01) Garcia-Palomares, Ubaldo M.; Pachón de la Cruz, Alvaro
This article approaches the dynamic resource allocation problem for the downlink of a wireless mobile communication system (WMCS). The article defines the architecture and functions of the global resource scheduler, as well as the quality index for scheduling, the signal to interference-plus-noise ratio (SINR). The proposed approach divides the scheduling task into two components: a distributed one, with local, short-term scope; and a centralized one, with global, medium-term scope. The optimization model considers a set of slack variables for guaranteeing feasibility. This allows the service provider to fully satisfy the users' service demands. The model type is mixed, non-linear, which demands large computational power for an exact solution. So an approximate strategy is used, in order to decouple the search space.
Post-chikungunya chronic inflammatory rheumatism: Results from a retrospective follow-up study of 283 adult and child cases in La Virginia, Risaralda, Colombia
(F1000 Research Ltd., 2016-12-25) Ramírez Jaramillo, Valeria
Objective: There are limited studies in Latin America regarding the chronic consequences of the Chikungunya virus (CHIK), such as post-CHIK chronic inflammatory rheumatism (pCHIK-CIR). We assessed the largest cohort so far of pCHIK-CIR in Latin America, at the municipality of La Virginia, Risaralda, a new endemic area of CHIK in Colombia. Methods: We conducted a cohort retrospective study in Colombia of 283 patients diagnosed with CHIK that persisted with pCHIK-CIR after a minimum of 6 weeks and up to a maximum of 26.1 weeks. pCHIK cases were identified according to validated criteria via telephone. Results: Of the total CHIK-infected subjects, 152 (53.7%) reported persistent rheumatological symptoms (pCHIK-CIR). All of these patients reported joint pains (chronic polyarthralgia, pCHIK-CPA), 49.5% morning stiffness, 40.6% joint edema, and 16.6% joint redness. Of all patients, 19.4% required and attended for care prior to the current study assessment (1.4% consulting rheumatologists).
Prevalencia de trastornos mentales en una población que demanda servicios de salud en una IPS de baja complejidad y su asociación con la ideación suicida y la discapacidad percibida
(Universidad de Antioquia, Facultad Nacional de Salud Pública, 2012-06-20) Rincón Hoyos, Hernán Gilberto
Conocer los trastornos mentales más frecuentes y el impacto en la percepción de discapacidad e ideación suicida en una Institución prestadora de servicios de salud de baja complejidad en Cali. Metodología: se realizó un estudio transversal con 254 pacientes a los que se les aplicó el instrumento prime-md. En el análisis se utilizó estadística descriptiva para determinar los trastornos más frecuentes y un análisis múltiple por regresiones logística y de Poisson con varianza robusta para determinar la influencia de los trastornos mentales en la discapacidad e ideación suicida. Resultados: la mayoría de los pacientes eran del sexo femenino, adultos jóvenes y maduros. La depresión estuvo presente en 66.8% de los casos, seguido del trastorno de somatización y la ansiedad. Casi la mitad de los pacientes habían tenido ideas suicidas alguna vez en la vida y 3 de cada 4 refirieron algún tipo de discapacidad. Después de ajustar por covariables, los trastornos ansiosos-depresivos mostraron una alta asociación con la ideación suicida y la discapacidad percibida, que es sobrestimada por la regresión logística. Conclusión: la depresión y la ansiedad son los trastornos mas frecuentes y tienen una alta asociación con la ideación suicida y la discapacidad y es por esto necesario realizar tamizaciones en la atención del adulto en servicios de baja complejidad. Se recomienda considerar el uso de la regresión de Poisson con varianza robusta en los estudios transversales en los servicios de salud.
Prevalencia y factores asociados a la adherencia al tratamiento no farmacológico en pacientes con hipertensión y diabetes en servicios de baja complejidad
(Facultad Nacional de Salud Pública, 2015-05-15) Méndez P., Fabián
Objective: to analyze avoidable mortality between 1998 and 2007 in the border states of Northern Mexico to evaluate, indirectly, the quality of the region's health care services. Methodology: the information on mortality provided by the National Health Information System (sinais) was analyzed. The unit of analysis was the basic cause of death. The cause was coded in accordance with the ICD-10.Avoidable mortality was classified according to Gomez’s death causes catalog. Likewise, an exploratory analysis was conducted which focused on the relationship between avoidable mortality and eligibility and the socioeconomic level of the municipalities in which the deaths took place.
Prevalencia y factores de riesgo para infecciones del tracto urinario de inicio en la comunidad causadas por Escherichia coli productor de betalactamasas de espectro extendido en Colombia
(Elsevier España, 2016-11-01) Blanco Pico, Víctor Manuel
Introduction Urinary tract infections (UTI) are common in the community. However, information of resistant isolates in this context is limited in Latin America. This study aims to determine the prevalence and risk factors associated with community-onset UTI (CO-UTI) caused by extended-spectrum β-lactamase (ESBL)-Producing Escherichia coli in Colombia. Materials and methods A case-control study was conducted between August and December of 2011 in three Colombian tertiary-care institutions. All patients who were admitted to the Emergency Department with a probable diagnosis of CO-UTI were invited to participate. All participating patients were asked for a urine sample. ESBL confirmatory test, antibiotic susceptibility, and molecular epidemiology were performed in these E.
Safety of Parecoxib in Asthmatic Patients with Aspirin-Exacerbated Respiratory Disease
(2011-09-01) Serrano Reyes, Carlos Daniel
BACKGROUND Aspirin-exacerbated respiratory disease (AERD) affects a subset of patients with asthma. Cyclooxygenase 2 inhibitors are a safe alternative in patients with AERD. Parecoxib is the first cyclooxygenase 2 selective drug for parenteral administration, especially useful after surgery thanks to its analgesic power. The aim of the study is to assess the tolerance of parecoxib (Dynastat; Pfizer) given by intramuscular route in patients with AERD. METHODS Patients evaluated were referred to the Pneumology and Respiratory Allergy Department of the Hospital Clinic (Barcelona, Spain) for asthma exacerbations precipitated by 2 or more different non-steroidal anti-inflammatory drugs (NSAIDs). AERD was confirmed by a nasal challenge test with aspirin. Patients were challenged with parecoxib, and urine samples were collected to measure the leukotriene E(4) concentration. RESULTS Ten patients were challenged with parecoxib. No symptoms were reported with any of the administered doses, and there were no signs of immediate or delayed hypersensitivity. There were no alterations in the forced expiratory volume in 1 s or in acoustic rhinometry measurements. No significant differences between leukotriene E(4) levels were detected. CONCLUSION The drug was well tolerated by all patients, with no adverse reactions. This lack of reactions found in our study supports the fact that parecoxib could be a safe alternative in postsurgery analgesia in NSAID-intolerant asthma patients.
¿Sería útil la depuración de los trastornos mentales comunes en pacientes hiperfrecuentadores de servicios de salud en cuidado primario?
(Asociacion Colombiana de Psiquiatria, 2012-10-01) Rincón Hoyos, Hernán Gilberto
La hiperfrecuentación de servicios de salud constituye un problema para los pacientes, la familia y las instituciones. Este trabajo busca determinar la frecuencia y las características de los trastornos mentales comunes en pacientes hiperfrecuentadores de servicios que acudieron con síntomas y signos imprecisos a una institución prestadora de servicios de cuidado primario en la ciudad de Cali (Colombia) en 2007
Severe hypoalbuminemia secondary gastric bypass. Revisional surgery to normal anatomy
(Springer Verlag, 2015-08-01) Dorado, Evelyn
Artículo de la cirujana bariátrica y profesora colombiana, doctora Evelin Astrid Dorado Alban que ejerce en la Clínica Fundación Valle del Lili de Cali. Especializada en su documento de métodos bariáticos de comprobada eficiencia (Manga gástrica o bypass gástrico, balón intragástico), como uno de los procedimientos para reducir peso de forma rápida y controlada; para evitar que el sobre peso sea causa de muchas enfermedades y de baja autoestima, ya que la obesidad es considerada como un detonante de otras enfermedades de riesgo que compromete seriamente la calidad de una persona, como ejemplo, diabetes, hipertensión, depresión e incluso algunos tipos de cáncer.
Solitary intracranial tuberculoma mimicking a malignant tumor in a patient without tubercular lesions or a history of disease: A case report
(2013-05-01) Sua, Luz Fernanda; Bravo, Luis E.
Cerebral tuberculoma is a rare cause of intracranial mass. In Latin America and Colombia where tuberculosis is endemic, it represents between 5 and 30% of brain tumours. A 53-year-old Colombian woman was admitted to a third-level hospital in Cali, Colombia, after reporting loss of consciousness, headache, paresthesia, and flight of ideas for a two-week period. Imaging studies showed a left frontal mass of malignant appearance whose first possible diagnosis was metastatic neoplasiaorglioma. With the initial results, absence of history of chronic infectious diseases and a history of thyroidectomy, a surgical procedure was carried out and a histopathological and molecular evaluation was conducted. The pathology report noted necrotizing granulomatous inflammation and tissue staining and molecular tests for detection of M. tuberculosis were positive and the patient was managed with anti-tubercular treatment. Intracranial masses are frequently targeted as a malignant neoplastic disease for surgical treatment. Considering an infectious etiology must be a diagnostic option. © 2013 Association of Basic Medical Sciences of FB&H.

Examinar

Examinando Nuevo conocimiento - FVL por Materia "Ciencias socio biomédicas"