Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates.
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Echeverri Junca, Gabriel Jaime
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Wiley
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BACKGROUND: CD154 blockade-based immunosuppression successfully prevents both humoral and cellular adaptive immune responses in baboons receiving α1,3-galactosyltransferase gene-knockout (GTKO) pig organs. Using a GTKO pig artery transplantation model in baboons, we evaluated the efficacy of CD28/B7 costimulatory pathway blockade in comparison with CD154 blockade.
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Ciencias socio biomédicasAnticuerposTrasplanteArteriaXenotrasplantes
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Medical sciences
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Except where otherwised noted, this item's license is described as Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)