Drug-induced lupus in anti-TNF-alpha therapy and its treatment with rituximab

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2012-10-01
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Springer Heidelberg
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Resumen
We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction of rituximab. Through this intervention, we observed a very good control of the activity of both DIL and RA without additional adverse reactions.
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Artritis reumatoide, Lupus, Rituximab, Medicina, Ciencias socio biomédicas, Biomedical sciences
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http://dx.doi.org/10.1007/s00296-011-2137-y
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0172-8172