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Ítem Epidermal Growth Factor Receptor Mutation In Patients With Non-Small Cell Lung Carcinoma In Fundacion Valle Del Lili, A University Hospital Of Reference In Latin America(American Lung Association, 2016-01-01) Fernández, LilianaEpidermal Growth Factor Receptor (EGFR) exon 19-deletion and exon 21 L858R mutation is found in 10% of Non-Small Cell Lung Carcinoma (NSCLC) in Caucasians and in 20 to 40% in Asians. The use of Tyrosine Kinase Inhibitors (TKI) in these genetic alterations has demonstrated a greater response and progression free survival in 9-15 months. Objective: To describe the experience in EGFR identification in Fundación Valle del Lili (FVL). Materials and Methods Between June/2013 and Sep/2015, 95 samples were analyzed. A microdissection of tumor areas was performed as well as DNA extraction with QIAamp FFPE Kit(Qiagen®) and amplification of exons 18, 19, 20 and 21 by PCR. It was visualized through microfluidic electrophoresis with Agilent Bioanalyzer® System. Results 98 samples were analyzed. Amplified DNA was obtained in 97% (95) of the cases. The mean age was 65,4±12 years, 63,2% (60) females and 36,8% (35) males. The mutation was observed in 25% (24), exon 19 in 10,5% and exon 21 in 14,7%. 83,1% of the tumors were adenocarcinomas, 70,5% in stage IV and 29% of the cases with a mutation was receiving TKI. Mortality was 14,7% .Ítem Expression Of Protein Kinase Eml4-Alk Gene In Non-Small Cell Lung Cancer In Fundacion Valle Del Lili, A University Hospital Of Reference In Latin America(American Thoracic Society, 2016-01-01) Restrepo, Juan G.Between 2-5% of patients with Non-Small Cell Lung Cancer (NSCLC), younger tan 50 years, present ALK (Anaplastic Lymphoma Kinase) and EML4 (Echinoderm Microtubule-associated protein Like 4) gene fusions causing inversion in chromosome2.Ítem Indications, Results And Complications Of Flexible Bronchoscopy In The Intensive Care Unit Of Fundacion Valle Del Lili, A University Hospital Of Reference In Latin America(American Lung Association, 2016-01-01) Muñoz, Carlos A.; Sua, Luz F.; Granados, Marcela; Fernández, LilianaIn the present, the flexible bronchoscopy (FB) has become the procedure of election to explore the airways fue to its diagnostic and therapeutic capacity in pulmonary pathology. In the critically ill patient this tool gains advantage since it provides the availability of being used at the bedside with few complications. In this study we describe the indications, results and complications associated to the performance of FB in the Intensive Care Unit of Fundación Valle del Lili, a University Hospital Reference in Cali, Colombia during 2013.