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Ítem Epidermal Growth Factor Receptor Mutation In Patients With Non-Small Cell Lung Carcinoma In Fundacion Valle Del Lili, A University Hospital Of Reference In Latin America(American Lung Association, 2016-01-01) Fernández, LilianaEpidermal Growth Factor Receptor (EGFR) exon 19-deletion and exon 21 L858R mutation is found in 10% of Non-Small Cell Lung Carcinoma (NSCLC) in Caucasians and in 20 to 40% in Asians. The use of Tyrosine Kinase Inhibitors (TKI) in these genetic alterations has demonstrated a greater response and progression free survival in 9-15 months. Objective: To describe the experience in EGFR identification in Fundación Valle del Lili (FVL). Materials and Methods Between June/2013 and Sep/2015, 95 samples were analyzed. A microdissection of tumor areas was performed as well as DNA extraction with QIAamp FFPE Kit(Qiagen®) and amplification of exons 18, 19, 20 and 21 by PCR. It was visualized through microfluidic electrophoresis with Agilent Bioanalyzer® System. Results 98 samples were analyzed. Amplified DNA was obtained in 97% (95) of the cases. The mean age was 65,4±12 years, 63,2% (60) females and 36,8% (35) males. The mutation was observed in 25% (24), exon 19 in 10,5% and exon 21 in 14,7%. 83,1% of the tumors were adenocarcinomas, 70,5% in stage IV and 29% of the cases with a mutation was receiving TKI. Mortality was 14,7% .Ítem Primary Lung Cystic Adenoid Tumor With Extensive Involvement Of The Right Lung And Distal Trachea Treated With Tracheal Sleeve Pneumonectomy: A Case Report(American Lung Association, 2016-01-01) Fernández, LilianaCystic adenoid carcinoma is a tumor with low-grade malignancy of slow growth original from salivary glands, which can appear in the central airway and extend to the lung. Even though its slow growth and discrete invasion, its localization may cause obstruction with severe compromise, we present the case of a patient with right lung cystic adenoid tumor with invasion of the carina, distal trachea and contralateral nodules treated with pneumonectomy and carinal resection with an adequate response