Efficacy and safety of anti-interleukin 6 receptor monoclonal antibody (tocilizumab) in Colombian patients with Takayasu arteritis.
| dc.audience | Comunidad Universidad Icesi – Investigadores | |
| dc.citation.issue | 3 | |
| dc.citation.volume | 20 | |
| dc.contributor.author | Cañas Dávila, Carlos Alberto | spa |
| dc.coverage.spatial | Philadelphia de Lat: 33 56 00 N degrees minutes Lat: 33.9333 decimal degrees Long: 085 32 00 W degrees minutes Long: -85.5333 decimal degrees | |
| dc.date.accessioned | 2015-10-14T21:57:27Z | |
| dc.date.available | 2015-10-14T21:57:27Z | |
| dc.date.issued | 2014-04-01 | |
| dc.description.abstract | Purpose: The aim of this study was to describe the efficacy and safety of anti–interleukin 6 receptor antibody (tocilizumab [TCZ]) in patients with severe or refractory Takayasu arteritis (TA). Methods: We describe 8 Colombian patients with severe and/or refractory TA treated with TCZ during a period of at least 9 months. Clinical, radiological, biological, and associated treatments were evaluated before, during, and after TCZ infusions. Results: The median age at evaluation was 31 years (12–43 years). All patients were female and experienced clinical and biological improvement, in addition to a corticosteroid-sparing effect from a median dose of 50 mg/d at baseline (30–60 mg/d) to 6.25 mg/d (2.5–10 mg/d) at 9 months. In 4 cases, in which imaging studies were available, an improvement was observed. | spa |
| dc.format.extent | 4 pàginas | |
| dc.format.medium | Digital | spa |
| dc.format.mimetype | application/pdf | |
| dc.identifier.doi | http://dx.doi.org/10.1097/RHU.0000000000000098 | |
| dc.identifier.instname | instname:Universidad Icesi | |
| dc.identifier.issn | 1076-1608 | |
| dc.identifier.other | http://journals.lww.com/jclinrheum/Abstract/2014/04000/Efficacy_and_Safety_of_Anti_Interleukin_6_Receptor.2.aspx | spa |
| dc.identifier.reponame | reponame:Biblioteca Digital | |
| dc.identifier.repourl | repourl:https://repository.icesi.edu.co/ | |
| dc.identifier.uri | http://hdl.handle.net/10906/78520 | |
| dc.language.iso | eng | eng |
| dc.publisher | Lippincott, Williams & Wilkins | spa |
| dc.publisher.department | Departamento de Ciencias Básicas Médicas | spa |
| dc.publisher.faculty | Facultad Ciencias de la Salud | spa |
| dc.publisher.place | Philadelphia | |
| dc.publisher.program | Medicina | spa |
| dc.relation.citationendpage | 129 | |
| dc.relation.citationstartpage | 125 | |
| dc.relation.ispartof | Journal of Clinical Rheumatology, Vol. 20, No. 3 -2014 | |
| dc.rights | EL AUTOR, expresa que la obra objeto de la presente autorización es original y la elaboró sin quebrantar ni suplantar los derechos de autor de terceros, y de tal forma, la obra es de su exclusiva autoría y tiene la titularidad sobre éste. PARÁGRAFO: en caso de queja o acción por parte de un tercero referente a los derechos de autor sobre el artículo, folleto o libro en cuestión, EL AUTOR, asumirá la responsabilidad total, y saldrá en defensa de los derechos aquí autorizados; para todos los efectos, la Universidad Icesi actúa como un tercero de buena fe. Esta autorización, permite a la Universidad Icesi, de forma indefinida, para que en los términos establecidos en la Ley 23 de 1982, la Ley 44 de 1993, leyes y jurisprudencia vigente al respecto, haga publicación de este con fines educativos. Toda persona que consulte ya sea la biblioteca o en medio electrónico podrá copiar apartes del texto citando siempre la fuentes, es decir el título del trabajo y el autor. | spa |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.coar | http://purl.org/coar/access_right/c_abf2 | |
| dc.rights.license | Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject.proposal | Arteritis de Takayasu | spa |
| dc.subject.proposal | Tratamiento | spa |
| dc.subject.proposal | Ciencias socio biomédicas | spa |
| dc.subject.proposal | Biomedical sciences | spa |
| dc.subject.proposal | Medicina | spa |
| dc.subject.proposal | Interleukin-6 | spa |
| dc.subject.proposal | Reumatología | spa |
| dc.title | Efficacy and safety of anti-interleukin 6 receptor monoclonal antibody (tocilizumab) in Colombian patients with Takayasu arteritis. | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | |
| dc.type.coarversion | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |
| dc.type.driver | info:eu-repo/semantics/article | eng |
| dc.type.local | Artículo | spa |
| dc.type.version | info:eu-repo/semantics/publishedVersion |
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