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Ítem Análisis de la distribución espacial y temporal de los defectos congénitos registrados entre 2004 y 2008 en un hospital de tercer nivel en Cali, Colombia(Universidad del Valle, 2011-01-01) Cuartas, Daniel ElíasObjective: To describe the spatial and temporal distribution of major birth defects and to identify clusters at spatial, temporal and space-temporal levels. Methods: A descriptive study was developed about the space and time distribution of defects registered in Cali between March 2004 and October 2008 using principles of spatial statistics, namely the spatial data exploratory analysis. Results: Higher case density and prevalence was observed among neighborhoods of eastern Cali. Three districts («communes») of the 21 in the city showed a larger probability (50 to 100% larger) of major birth defects. Significant clusters (p<0.05) were proven in spatial, temporal and space-temporal analysis. Conclusions: Birth defects were confirmed clustered in several communes at the poorest areas of the city. Occurrence of defects in this area may be associated, at least in part, to social and environmental inequities. © 2011 Universidad del Valle, Facultad de Salud.
Ítem Biomarkers of cardiovascular disease are increased in untreated chronic periodontitis: a case control study.(Wiley, 2014-03-01) Ariza Araujo, Yoseth JesualdoBackground: The aim of this study was to evaluate the endothelial function, systemic inflammatory biomarkers and subgingival microbial profile associations in patients with and without periodontal disease.Ítem Retraso en el diagnóstico de un cuadro grave de enfermedad de Huntington juvenil: caso clínico(Sociedad Argentina de Pediatria, 2014-01-01) Ariza Araujo, Yoseth JesualdoHuntington's disease is a neurodegenerative disease that is clinically manifested as mood and personality changes, loss of cognitive functions and choreiform movements. The pattern of inheritance is autosomic dominant. It is due to the gradual expansion of a cytosine, adenine, guanine trinucleotide in a gene that codifies the protein Huntington. The molecular diagnosis must be performed to confirm the diagnosis. Genetic counseling must be carefully done due to the high suicide risk among these patients. We present the case of a fourteen-year-old male with a severe disease, poor social support and an unclear pattern of inheritance.Ítem Rapid, severe neurological impairmentassociated with paraneoplastic cerebellardegeneration and anti-Yo antibodies(Elsevier, 2014-03-01) Ariza Araujo, Yoseth Jesualdo12The patient was a 69-year-old woman treated at ourhospital for left gaze deviation, generalised hypotonia fol-lowed by limb hypertonia, and loss of consciousness lastingapproximately 5 minutes. Medical history included arterialhypertension and hypothyroidism, both of which were con-trolled.Ítem Deterioro neurológico rápido y severo asociado a degeneración cerebelosa paraneoplásica con anticuerpos anti-Yo positivos(Elsevier, 2014-03-01) Ariza Araujo, Yoseth JesualdoSe trata de una mujer de 69 años, que consulta en nuestro hospital por cuadro de desviación de la mirada a la izquierda, con pérdida de la consciencia aproximadamente 5 min, hipotonía generalizada y luego hipertonicidad en extremidades: Como antecedentes tenía hipertensión arterial e hipotiroidismo controlados, venía con pérdida de peso 8 kg en 6 meses y una semana previa al ingreso inició cuadro de dificultad para la marcha, vértigo, visión borrosa y dificultad para hablar. En la exploración, signos vitales sin alteraciones, paciente alerta, orientada, disártrica, con dificultad para obedecer órdenes, ojos con movimientos sacádicos y nistagmo vertical, con marcada dismetría mayor izquierda en el test dedo nariz; la prueba talón-pierna-rodilla no pudo ser realizada; los reflejos tendinosos, los pares craneanos y la sensibilidad, sin alteraciones