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Ítem Synthesis, Characterization And Application In Controlled Drug Release Of Chitosan Hydrogels Obtained From Aspergillus Niger.(European Polymer Federation, 2011-06-26) XII Congress of the Specialized Group of PolymersNora Elena Valderruten Posso, PhD Universidad del país Vasco, 2001. En Ciencias Químicas, Maestría Universidad del Valle, Posgrado Universidad del Valle en Biología Química, profesora de tiempo completo de la Universidad Icesi del Departamento Académico Ciencias Químicas de la Facultad de Ciencias Naturales y miembro del comité asesor, - trabajps dirigidos/tutorias- trabajos de grado de pregrado, jurado de comité evaluación- miembro del consejo de la Facultad de Ciencias Naturales y coordinadora de cursos de Química Orgánica. Sus trabajos de investigación y desarrollo en la obtención de polimeros biodegradables apartir de ácido grasos de origen vegetal, obtención de materiales compuestos Core-Shell mediante inmovilizacion de catalizadores metalogénicos, obtención de materias polimetricos inteligentes a partir de un subproducto industrial con potencial en la industria farmacéuticas y otras. Synthesis, Characterization And Application In Controlled Drug Release Of Chitosan Hydrogels Obtained From Aspergillus Niger.Ítem Synthesis and characterization of chitosan hydrogels cross-linked with dicarboxylic acids(Elsevier, 2014-11-01) Zuluaga, Héctor FabioChitosan hydrogels cross-linked with dicarboxylic acids were prepared. Succinic, glutaric and adipic acid were used as cross-linking agents, the goal being to compare the effect of the length of the chain on the behavior of the material obtained. The swelling properties were studied at different pHs and temperatures, and it was discovered that these properties depend particularly on the pH of the environment. Creep-recovery and stress-relaxation studies were performed to determine mechanical properties and the chitosan/succinic acid hydrogels exhibited a completely viscous behavior. Thermal studies were carried out using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). DSC results revealed that the materials obtained are completely amorphous. Acetaminophen was used as a positive control for the release kinetics studies. Upon fitting the results to a specific mathematical model, it was determined that the release process is controlled by diffusion and relaxation of the polymer network.Ítem Síntesis y caracterización de hidrogeles interpenetrados de quitosano/PNIPA(Universidad Icesi, 2012-08-29) Valderruten Posso, Nora Elena; Ruiz Durantez, Eduardo; Katime, Issa A.; Agudelo, JonathanUna red interpenetrada (IPN) consiste en la combinación de dos redes poliméricas diferentes, sin que haya enlaces covalentes entre ellas; de esta forma se consigue una mezcla física que contiene polímeros entrecruzados. Este tipo de polímeros se prepara por el entrecruzamiento simultáneo o secuencial de dos sistemas diferentes y genera materiales que exhiben las propiedades de los dos componentes. El quitosano es un polímero biodegradable, biocompatible y sensible al pH del medio. Por otro lado, la Poli(N-isopropilacrilamida) es un polímero termosensible.Ítem Síntesis y caracterización de materiales absorbentes interpenetrados a partir de polímeros sensibles al pH y temperaturas.(Universidad Icesi, 2011-11-00) Ruiz Durantez, Eduardo; Valderruten Posso, Nora Elena; Valverde, J.D.; Zuluaga, F.Chitosan hydrogels cross-linked with dicarboxylic acids were prepared. Succinic, glutaric and adipic acid were used as cross-linking agents, the goal being to compare the effect of the length of the chain on the behavior of the material obtained. The swelling properties were studied at different pHs and temperatures, and it was discovered that these properties depend particularly on the pH of the environment. Creep-recovery and stress-relaxation studies were performed to determine mechanical properties and the chitosan/succinic acid hydrogels exhibited a completely viscous behavior. Thermal studies were carried out using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). DSC results revealed that the materials obtained are completely amorphous. Acetaminophen was used as a positive control for the release kinetics studies. Upon fitting the results to a specific mathematical model, it was determined that the release process is controlled by diffusion and relaxation of the polymer network.