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Ítem Doble aneuploidía (trisomía X, trisomía 18) en una recién nacida con fenotipo de trisomía 18(2013-07-01) Pachajoa Londoño, Harry MauricioWe report the case of a newborn girl with a double trisomy, with a chromosome complement 48, XXX,+ 18, with Edwards syndrome phenotype (trisomy 18). The clinical feature included intrauterine growth retardation, dysmorphic facies, hand with overlapping fingers, ventricular septal defect, pulmonary stenosis and left clubfoot. A review of the literature and discussion of previously reported cases is made.
Ítem Relationship between maternal and newborn endothelial function and oxidative stress(Wiley, 2015-12-01) Echeverri, Isabella; Aguilar de Plata, Cecilia; Mateous, Julio César; Suárez Ortegon, Milton Fabian; Mosquera, Mildrey; Ortega Ávila, José Guillermo; Castillo Giraldo, Andrés Orlando; Jiménez, EliécerObjective To evaluate the Relationship between maternal and newborn endothelial function and oxidative stress. Methods Forty-three pregnant women and their offspring were evaluated. As markers of endothelial function, the flow-mediated dilation (FMD) was measured in pregnant women in the second and third trimesters, and nitric oxide (NO) was quantified in the endothelial cells of the umbilical cord vein. Malondialdehyde (MDA), as a marker of oxidative stress, was measured in the maternal plasma (second and third trimesters) and plasma from umbilical cord blood. Gestational age and birth weight were recorded. Correlations between variables were estimated, and adjustments were made for specific gestational week of measurement, gestational age at birth, and complications during pregnancy and/or at delivery.