2024-11-01, Rouvinski, Vladimir, Silva Chica, Laura

El contenido que compone la presente obra permite hacer honra a la memoria de estos inmigrantes japoneses, sus dificultades naturales en el proceso migratorio y adaptativo, el impacto y sus consecuentes aportes en Colombia, al igual que el papel de sus descendientes Nikkeis a la nación. Este esfuerzo fue realizado por los y las estudiantes de los cursos de pregrado “Historia Política Internacionales” y “Pensamiento Crítico Latinoamericano” de la Facultad de Ciencias Humanas de la Universidad Icesi, que llevaron a cabo encuentros y entrevistas con miembros de varias de las familias que migraron desde Japón el siglo pasado, y más adelante tejieron narraciones, a modo de relatos, para hilar historias, hechos y anécdotas [Santiago Martínez Villareal]. Los relatos aquí recopilados reflejan la resistencia y la adaptación de los migrantes japoneses, quienes, a pesar de las dificultades, han dejado una huella imborrable en nuestra identidad nacional y regional. Al abordar temas como la innovación de técnicas agrícolas, comercio, convivencia y la fusión de tradiciones culturales y culinarias, esta obra invita a la reflexión sobre la diversidad que conforma nuestro país, así como sobre el espíritu empresarial que caracteriza a la comunidad japonesa colombiana [Esteban Piedrahita Uribe].

2024-06-12, González Gutiérrez, José Stevens, Valderruten Posso, Nora Elena, Mora Guerrero, Carolina Del Pilar, Pinillos, Juan Fernando, Campo, Claudia Jimena, Bolaños, Jhony Andrés, Arboleda, María Alejandra, Urbano, John Jairo, Chaur, Manuel, Sanmiguel, Bryan Alexis, Gómez, Ana Lucía

Chitosan (QN) is a naturally occurring, biodegradable, and biocompatible polysaccharide. It has shown great versatility in the pharmaceutical field due to its various characteristics. QN is commonly extracted from crustaceans, but other sources exist, such as the mycelium of filamentous fungi (e.g., Aspergillus niger). This study aimed to evaluate chitosan obtained from A. niger as a coating for a modified-release pharmaceutical dosage form (MRDF). To achieve this, 3 QN extractions were performed from A. niger mycelium. The obtained QN samples were analyzed for the degree of deacetylation (%DDA) by potentiometric titration and were characterized by Infrared spectroscopy (FTIR) and differential scanning calorimetry (DSC). The %DDA values for extractions #1, #2, and #3 were 48.23 %, 48.32 %, 41.99 %, 39.30 %, 39.71 %, 39.64 %, 39.82 %, 48.21 %. QN from extraction #3 with an average %DDA of 41.34 % was selected to coat tablets. Five formulations were prepared, varying the polymer concentration, vehicle, and the addition of modulating excipients. It was observed that formulations with alcoholic vehicle and excipients showed better spraying. The coated tablets were subjected to a dissolution test, which showed rapid tablet disintegration and coating release. This was due to the partial coating of the tablets. It was concluded that the obtained material corresponds to chitosan, but a greater amount of coating is required to ensure modified release.

2024-06-12, Cerón Rojas, Natalia, Osorio Vargas, Daniela, Montoya P., Guillermo L., Montoya Peláez, Guillermo León, Montoya Peláez, Guillermo León

Green tea is obtained from the species Camellia sinensis, which has high contents of catechins, possessing antioxidant, anti-inflammatory, and anticancer properties. Among the most studied is epigallocatechin-gallate (EGCG) as it is found in greater proportion, considered the most potent bioactive compound in green tea, and due to its antimicrobial effects, it can contribute to oral health. Therefore, the objective of the project was to develop experimental extraction and drying conditions for premium green tea leaves to obtain high EGCG contents for application in a magistral formulation. To achieve this, a protocol for the extraction and drying of premium green tea was developed to contain high percentages of EGCG, which was established by standardizing an analytical method for its evaluation; and finally, the incorporation of lyophilized tea into a magistral formulation was evaluated, as well as its stability through a forced degradation study. Finally, the content of EGCG and caffeine was 1.58 mg/g and 82.31 mg/g in the green tea powder, respectively; in the forced degradation studies, no decrease in concentration over time or incorporation of the tea was observed, but after changes in sample preparation before entering the equipment for evaluation, a slight degradation of EGCG was observed. Therefore, the green tea extraction conditions were optimized, and simultaneously, issues in the preparation protocol of the magistral formulation were evidenced.

2024-06-12, Bolaños Bolaños, María Laura, López Martínez, Salomé, Acosta Santamaria, Angela Patricia, Angulo Nieva, Diana Constanza

El presente proyecto se centra en una revisión de alcance que identifica cuatro principales áreas de aplicación de la telefarmacia: hospitalaria, ambulatoria, comunitaria y transición del cuidado. En estos contextos, se utilizaron diversas intervenciones, destacando las LT como la metodología más frecuentemente empleada. En general, los resultados de la telefarmacia fueron predominantemente positivos en los casos analizados. En Colombia, la implementación de la telefarmacia dependerá del ámbito específico y de las enfermedades a tratar, siendo especialmente útil para la gestión de enfermedades crónicas. Los objetivos de este estudio son: primero, describir las características de implementación y su posible efecto en el acceso y mejoramiento de los servicios farmacéuticos; segundo, describir el posible aporte de la telefarmacia en el seguimiento farmacoterapéutico a pacientes; tercero, describir el proceso de gestión del riesgo y el enfoque de SP; y cuarto, comparar los diferentes modelos de telefarmacia implementados, destacando sus características, ventajas, desventajas y percepción por parte del paciente.